Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1Rkuhn
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ralf Kuhn
MGI ID:	MGI:3785787
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1Rkuhn page

Germline Transmission:	Earliest citation of germline transmission: J:133638
Parent Cell Line:	IDG3.2 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S6/SvEvTac)F1

Allele Type:    Targeted (RMCE-ready) Mutation:    Insertion   Mutation details: This allele was created to facilitate insertion of vectors into the Rosa26 locus using recombinase-mediated cassette exchange. A splice acceptor followed by a pgk promoter driving an attP-flanked hygromycin selection gene was inserted into intron 1. Upon expression of C31 intergrase, the hyrgromycin cassette will be exchanged with a donor vector containing an attB-flanked cassette. (J:133638)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:133638 Hitz C, et al., Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference. Nucleic Acids Res. 2007;35(12):e90
All:	3 reference(s)