Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Col1a2-cre/ERT,-ALPP)7Cpd
Name:	transgene insertion 7, Christopher P Denton
MGI ID:	MGI:3785760
Synonyms:	Col1a2 Cre-ER, Col1a2CreERT, Col1a2-Cre-ER(T), Tg(Col1a2-cre/ERT)7Cpd, Tg(Col1a2-cre/ESR1)71Pcn, Tg(Col1a2-cre/ESR1)7Cpd
Transgene:	Tg(Col1a2-cre/ERT,-ALPP)7Cpd  Location: unknown
Alliance:	Tg(Col1a2-cre/ERT,-ALPP)7Cpd page

Strain of Origin:

(C57BL/6 x DBA/2)F2

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Col1a2-cre/ERT,-ALPP)7Cpd expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Col1a2   Mutation details: The Col1a2 enhancer was used to drive fibroblast-specific expression of a cre/ERT fusion followed by an IRES-human placental alkaline-phosphatase reporter. Two lines were created (lines 7 and 8) and line 7 was used in subsequent analysis. (J:134447)

Activity:	Tissue activity of this recombinase allele
Driver:	Col1a2 (species not specified) Summary of all recombinase alleles driven by Col1a2. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available

Original:	J:134447 Zheng B, et al., Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis. Am J Pathol. 2002 May;160(5):1609-17
All:	97 reference(s)