Gene Expression Data
Assay Details
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Assay
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Reference:
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J:132031
Wong RL, et al., Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum Mol Genet. 2008 Feb 15;17(4):587-601
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3785606
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Gene symbol:
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Nkx2-9
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Gene name:
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NK2 homeobox 9
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Probe:
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Nkx2-9 cDNA5
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
7A mutant WM:
(close  )
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: neural tube |
Present |
Regionally restricted |
7A Nkx2-9 Gt/Gt WM
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The change in gene expression was restricted to the neural tube. In the mutant, expression was expanded and the upregulation appeared caudal to the forelimb bud.
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Specimen
7A WT WM:
embryonic day 9.5
(more  )
Specimen
7A WT WM:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: future spinal cord |
Present |
Regionally restricted |
7A Nkx2-9 WT WM
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Expression was detected in the ventral domain of neuronal progenitors that give rise to V3 interneurons.
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Specimen
7A mutant section:
(close )
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Genetic Background:
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involves: 129S5/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Fkbp8Gt(OST287985)Lex/Fkbp8Gt(OST287985)Lex
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: neural tube |
Present |
Regionally restricted |
7A Nkx2-9 Gt/Gt section
|
The change in gene expression was restricted to the neural tube. In the mutant, expression was expanded and the upregulation appeared caudal to the forelimb bud.
|
Specimen
7A WT section:
embryonic day 9.5
(more )
Specimen
7A WT section:
(close )
|
Genetic Background:
|
Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: future spinal cord |
Present |
Regionally restricted |
7A Nkx2-9 WT section
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Expression was detected in the ventral domain of neuronal progenitors that give rise to V3 interneurons.
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Analysis Tools
