Tg(PDGFB-EPO)322Zbz
Transgene Detail
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| Symbol: |
Tg(PDGFB-EPO)322Zbz |
| Name: |
transgene insertion 322, University of Zurich |
| MGI ID: |
MGI:3784780 |
| Synonyms: |
Tg21, TgN(PDGFBEPO)322Zbz |
| Transgene: |
Tg(PDGFB-EPO)322Zbz Location: unknown
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| Alliance: |
Tg(PDGFB-EPO)322Zbz page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(PDGFB-EPO)322Zbz expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
EPO (2056) |
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Mutation details: The transgenic construct consisted of the human erythropoietin cDNA adjoined to the human platelet derived growth factor B promoter. A four fold increase in EPO occurs in the brain but not in blood plasma.
(J:65257)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:65257 Ruschitzka FT, et al., Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11609-13 |
| All: |
10 reference(s) |
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Analysis Tools
