Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Stx1atm2Sud
Name:	syntaxin 1A (brain); targeted mutation 2, Thomas C Sudhof
MGI ID:	MGI:3784566
Synonyms:	Stx1atm1(ECFP)Sud
Gene:	Stx1a  Location: Chr5:135052336-135079954 bp, + strand  Genetic Position: Chr5, 74.95 cM
Alliance:	Stx1atm2Sud page

Germline Transmission:	Earliest citation of germline transmission: J:134023
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A targeting vector was designed to introduce a loxP-flanked ECFP transgene to exon 2 and an FRT-flanked neomycin drug resistance cassette to intron 1 of the gene. (Enhanced cyan fluorescence protein (ECFP) has been inserted into the amino terminal of the syntaxin 1A gene.) Targeted mice were crossed with an actin promoter-driven FLP strain to remove the neomycin cassette. (J:134023)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Stx1a Mutation:	25 strains or lines available

Original:	J:134023 Sudhof TC, Generation of an Stx1a mutant. MGI Direct Data Submission. 2008;
All:	4 reference(s)