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Gene Expression Data
Assay Details
Assay
Reference: J:127937 Bird AD, et al., Identification of glucocorticoid-regulated genes that control cell proliferation during murine respiratory development. J Physiol. 2007 Nov 15;585(Pt 1):187-201
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3778623
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen distal lung: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung Present Single cells 1A +/+ distal lung Expression is present in proliferating cells in the distal region of the lung.
TS26: lung mesenchyme Present Single cells 1A +/+ distal lung Expression is present in proliferating cells in the distal region of the lung.

Specimen distal lung: embryonic day 18.5; Nr3c1tm1Gsc/Nr3c1tm1Gsc (more )
Structure Level Pattern Image Note
TS26: lung Present Single cells 1A -/- distal lung Expression is present in proliferating cells in the distal region of the lung.
TS26: lung mesenchyme Present Single cells 1A -/- distal lung Expression is present in proliferating cells in the distal region of the lung. Staining is more abundant in the mutant compared to wild-type, particularly in the interstitial mesenchyme of the distal lung.

Specimen proximal airway: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung Present Single cells 1A +/+ proximal airway Expression is present in proliferating cells in the proximal region of the lung.

Specimen proximal airway: embryonic day 18.5; Nr3c1tm1Gsc/Nr3c1tm1Gsc (more )
Structure Level Pattern Image Note
TS26: lung Present Single cells 1A -/- proximal airway Expression is present in proliferating cells in the proximal region of the lung; the rate of proliferation is similar in mutants compared to wild type.

Specimen blood vessels: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: blood vessel Present Single cells 1A +/+ blood vessels Expression is present in proliferating cells in blood vessels of the lung.
TS26: lung Present Single cells 1A +/+ blood vessels Expression is present in proliferating cells in blood vessels of the lung.

Specimen blood vessels: embryonic day 18.5; Nr3c1tm1Gsc/Nr3c1tm1Gsc (more )
Structure Level Pattern Image Note
TS26: blood vessel Present Single cells 1A -/- blood vessels Expression is present in proliferating cells in blood vessels of the lung; the rate of proliferation is similar in mutants compared to wild type.
TS26: lung Present Single cells 1A -/- blood vessels Expression is present in proliferating cells in blood vessels of the lung; the rate of proliferation is similar in mutants compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory