Gene Expression Data
Assay Details
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Assay
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Reference:
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J:98502
Strumpf D, et al., Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development. 2005 May;132(9):2093-102
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3777423
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Gene symbol:
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Tjp1
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Gene name:
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tight junction protein 1
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Results
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Specimen
Not shown:
embryonic day 3.25; Cdx2tm1Fbe/Cdx2 +
(more  )
Note: This is an early blastocyst.
Specimen
Not shown:
(close  )
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Genetic Background:
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involves: ICR
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Mutant Allele(s):
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Cdx2tm1Fbe/Cdx2+
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Age:
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embryonic day 3.25
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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optical section
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Note:
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This is an early blastocyst.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS4: blastocyst |
Present |
Regionally restricted |
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This protein localizes to the tight junctions.
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Specimen
Not shown:
embryonic day 3.25; Cdx2tm1Fbe/ Cdx2tm1Fbe
(more )
Note: This is an early blastocyst.
Specimen
Not shown:
(close )
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Genetic Background:
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involves: ICR
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Mutant Allele(s):
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Cdx2tm1Fbe/Cdx2tm1Fbe
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Age:
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embryonic day 3.25
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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optical section
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Note:
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This is an early blastocyst.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS4: blastocyst |
Present |
Regionally restricted |
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This protein localizes to the tight junctions. Its localization appears grossly normal in mutants compared to non-mutant genotypes.
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Specimen
Not shown:
embryonic day 4.0; Cdx2tm1Fbe/Cdx2 +
(more )
Note: This is a late blastocyst.
Specimen
Not shown:
(close )
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Genetic Background:
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involves: ICR
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Mutant Allele(s):
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Cdx2tm1Fbe/Cdx2+
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Age:
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embryonic day 4.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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optical section
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Note:
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This is a late blastocyst.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS5: trophectoderm |
Present |
Regionally restricted |
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This protein localizes to the tight junctions.
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Specimen
Not shown:
embryonic day 4.0; Cdx2tm1Fbe/ Cdx2tm1Fbe
(more )
Note: This is a late blastocyst.
Specimen
Not shown:
(close )
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Genetic Background:
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involves: ICR
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Mutant Allele(s):
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Cdx2tm1Fbe/Cdx2tm1Fbe
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Age:
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embryonic day 4.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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optical section
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Note:
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This is a late blastocyst.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS5: trophectoderm |
Present |
Regionally restricted |
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This protein localizes to the tight junctions. In mutants the staining appears diffuse, suggesting the integrity of the epithelium is not maintained in the mutants.
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Analysis Tools