Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptrh2tm1Eruo
Name:	peptidyl-tRNA hydrolase 2; targeted mutation 1, Erkki Ruoslahti
MGI ID:	MGI:3775073
Synonyms:	Bit1flxNeo
Gene:	Ptrh2  Location: Chr11:86574900-86583283 bp, + strand  Genetic Position: Chr11, 51.82 cM
Alliance:	Ptrh2tm1Eruo page

Germline Transmission:	Earliest citation of germline transmission: J:131853
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An frt-flanked neo cassette with a 3' loxP site was inserted downstream of the open reading frame and an additional loxP site was inserted upstream of the open reading frame. Mice were commercially prepared by Ozgene. (J:131853)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptrh2 Mutation:	35 strains or lines available

Original:	J:131853 Kairouz-Wahbe R, et al., Anoikis effector Bit1 negatively regulates Erk activity. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1528-32
All:	2 reference(s)