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Aviltm1(ALPP)Fawa
Targeted Allele Detail
Summary
Symbol: Aviltm1(ALPP)Fawa
Name: advillin; targeted mutation 1, Fan Wang
MGI ID: MGI:3774413
Synonyms: AdvillinPLAP, AvilAP, AvilhPLAP
Gene: Avil  Location: Chr10:126836578-126856863 bp, + strand  Genetic Position: Chr10, 74.48 cM, cytoband D3
Alliance: Aviltm1(ALPP)Fawa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130971
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe open reading frame for human placental alkaline phosphatase and a floxed neo cassette was knocked into exon 2. The absence of transcript expression was confirmed by in situ hybridization. This is a null allele. (J:130971)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 71 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Avil Mutation:  46 strains or lines available
References
Original:  J:130971 Hasegawa H, et al., Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene. J Neurosci. 2007 Dec 26;27(52):14404-14
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory