Tg(APOE_i4,APOC1)81Mae
Transgene Detail
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Symbol: |
Tg(APOE_i4,APOC1)81Mae |
Name: |
transgene insertion 81, Nobuyo Maeda |
MGI ID: |
MGI:3768351 |
Synonyms: |
ApoE4-tg., E4-81, Tg(APOE*4,APOC1)81Mae |
Transgene: |
Tg(APOE_i4,APOC1)81Mae Location: unknown
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Alliance: |
Tg(APOE_i4,APOC1)81Mae page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(APOE_i4,APOC1)81Mae expresses
2 genes
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
APOC1 (341) |
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human |
APOE (348) |
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Mutation details: A human genomic clone containing the APOE*4 allele of the APOE gene, the APOC1 gene and the hepatocyte control region (HCR) located downstream of the APOC1 gene was used to create transgenic mice. Four transgenic lines were generated including lines 20, 43, 64, and 81.
(J:109197)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:109197 Xu PT, et al., Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiol Dis. 1996;3(3):229-45 |
All: |
20 reference(s) |
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