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Tg(APOE_i3,APOC1)453Mae
Transgene Detail
Summary
Symbol: Tg(APOE_i3,APOC1)453Mae
Name: transgene insertion 453, Nobuyo Maeda
MGI ID: MGI:3768343
Synonyms: ApoE3-tg., E3-453, Tg(APOE*3,APOC1)453Mae
Transgene: Tg(APOE_i3,APOC1)453Mae  Location: unknown  
Alliance: Tg(APOE_i3,APOC1)453Mae page
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(APOE_i3,APOC1)453Mae expresses 2 genes
 
Mutation detailsA human genomic clone containing the APOE*3 allele of the APOE gene, the APOC1 gene and the hepatocyte control region (HCR) located downstream of the APOC1 gene was used to create transgenic mice. Five transgenic lines were generated including lines 393, 414, 428, 437, and 453. (J:109197)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:109197 Xu PT, et al., Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiol Dis. 1996;3(3):229-45
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory