Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Nkx2-1-cre)2Sand
Name:	transgene insertion 2, Stewart Anderson
MGI ID:	MGI:3773076
Synonyms:	Nkx2-1BACCre, Nkx2.1-cre, Nkx2.1Cre, NKX2.1Cre, Tg(Nkx2-1-cre)1Qixu, Tg(Nkx2-1-cre)2Qixu, Ttf-1Cre
Transgene:	Tg(Nkx2-1-cre)2Sand  Location: unknown
Alliance:	Tg(Nkx2-1-cre)2Sand page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Nkx2-1-cre)2Sand expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Nkx2-1 (MGI:108067)   Mutation details: A mouse BAC clone containing the Nkx2-1 gene was engineered to express cre recombinase. Fifteen base pairs at the 5'end of exon 2 of the Nkx2-1 gene were replaced with a cre-poly(A) construct. The mutated BAC clone was then used to generate transgenic mice. This construct is expressed in brain, thyroid, pituitary, and lung, with telecephalic expression first detectable at E10.5. (J:131144)

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx2-1 (mouse) Summary of all recombinase alleles driven by Nkx2-1. Comparative matrix view of recombinase activities Alliance mouse Nkx2-1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

91 assay results 6 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:131144 Xu Q, et al., Fate mapping Nkx2.1-lineage cells in the mouse telencephalon. J Comp Neurol. 2008 Jan 1;506(1):16-29
All:	196 reference(s)