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Tg(CD2-Runx1)81Sata
Transgene Detail
Summary
Symbol: Tg(CD2-Runx1)81Sata
Name: transgene insertion 81, Masanobu Satake
MGI ID: MGI:3771952
Synonyms: Runt-Tg, Runx dn-Tg
Transgene: Tg(CD2-Runx1)81Sata  Location: unknown  
Alliance: Tg(CD2-Runx1)81Sata page
Transgene
origin
Strain of Origin:  C3H/HeN
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD2-Runx1)81Sata expresses 1 gene
 
Mutation detailsThe human CD2 promoter drives expression of a dominant interfering mouse DNA-binding domain of the Runx1 gene. In addition to line 81, lines 48 and 65 were also established. (J:66172)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:66172 Hayashi K, et al., Diminution of the AML1 transcription factor function causes differential effects on the fates of CD4 and CD8 single-positive T cells. J Immunol. 2000 Dec 15;165(12):6816-24
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory