Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc31a1tm2Djt
Name:	solute carrier family 31, member 1; targeted mutation 2, Dennis J Thiele
MGI ID:	MGI:3771147
Synonyms:	Ctr1flox
Gene:	Slc31a1  Location: Chr4:62278964-62310006 bp, + strand  Genetic Position: Chr4, 33.11 cM, cytoband C1-C2
Alliance:	Slc31a1tm2Djt page

Germline Transmission:	Earliest citation of germline transmission: J:129741
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted into intron 4 and an additional loxP site was inserted upstream of exon 1. The neo cassette was removed by cre-mediated recombination. (J:129741)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc31a1 Mutation:	40 strains or lines available

Original:	J:129741 Nose Y, et al., Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function. Cell Metab. 2006 Sep;4(3):235-44
All:	14 reference(s)