Tg(CMV-Atp2a2)CJ5Whd
Transgene Detail
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| Symbol: |
Tg(CMV-Atp2a2)CJ5Whd |
| Name: |
transgene insertion CJ5, Wolfgang H Dillmann |
| MGI ID: |
MGI:3771074 |
| Transgene: |
Tg(CMV-Atp2a2)CJ5Whd Location: unknown
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| Alliance: |
Tg(CMV-Atp2a2)CJ5Whd page
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| Strain of Origin: |
BALB/c x C57BL/6
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CMV-Atp2a2)CJ5Whd expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| rat |
Atp2a2 (29693) |
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Mutation details: This transgene expresses a rat Atp2a2 cDNA under the control of a human cytomegalovirus
immediate early enhancer linked to the chicken beta-actin minimal promoter. The transgene copy number is estimated to be 2, and the total amount of expressed RNA in heart ventricles is 2.6-fold higher than in control littermates. An additional transgenic line from founder CJ2 was also established.
(J:107873)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:107873 He H, et al., Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. J Clin Invest. 1997 Jul 15;100(2):380-9 |
| All: |
6 reference(s) |
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Analysis Tools
