Tg(Foxa3-Cdx2)1Khk
Transgene Detail
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| Symbol: |
Tg(Foxa3-Cdx2)1Khk |
| Name: |
transgene insertion 1, Klaus H Kaestner |
| MGI ID: |
MGI:3769381 |
| Synonyms: |
Foxa3/Cdx2 transgenic |
| Transgene: |
Tg(Foxa3-Cdx2)1Khk Location: unknown
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| Alliance: |
Tg(Foxa3-Cdx2)1Khk page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Foxa3-Cdx2)1Khk expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Cdx2 (MGI:88361) |
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Mutation details: Cdx2 expression was directed to the gastric mucosa in transgenic mice using cis-regulatory elements
of Foxa3. Ectopic protein expression of Cdx2 in the stomach was confirmed by immunohistochemistry using the Cdx2 antibody. The transgenic mice expressed Cdx2 protein throughout the epithelium of the glandular gastric mucosa with heterogeneous nuclear staining, which did not appear to be cell type-specific.
(J:75016)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:75016 Silberg DG, et al., Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology. 2002 Mar;122(3):689-96 |
| All: |
5 reference(s) |
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Analysis Tools
