Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(IGFBP2)1Miel
Name:	transgene insertion 1, John Miell
MGI ID:	MGI:3769995
Synonyms:	line tg1
Transgene:	Tg(IGFBP2)1Miel  Location: unknown
Alliance:	Tg(IGFBP2)1Miel page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(IGFBP2)1Miel expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human IGFBP2 (3485) Igfbp2  (MGI:96437)   Mutation details: The IGFBP-2 transgene (isolated from a human cosmid clone) contains the entire structural human IGFBP2 gene. This 39 kb transgene was microinjected into the pronucleus of FVB/N embryos. Two lines tg1 and tg2 were established and line tg1 was analyzed in detail. (J:121961)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:121961 Wheatcroft SB, et al., IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes. 2007 Feb;56(2):285-94
All:	1 reference(s)