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Kat8tm1Thl
Targeted Allele Detail
Summary
Symbol: Kat8tm1Thl
Name: K(lysine) acetyltransferase 8; targeted mutation 1, Thomas Ludwig
MGI ID: MGI:3769362
Synonyms: Kat8flox, mMofflox, Mofflox
Gene: Kat8  Location: Chr7:127511689-127525010 bp, + strand  Genetic Position: Chr7, 69.83 cM
Alliance: Kat8tm1Thl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128936
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt-flanked neo cassette with a 5' loxP site was inserted upstream of intron 1 and an additional loxP site was inserted downstream of exon 3. (J:128936)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat8 Mutation:  36 strains or lines available
References
Original:  J:128936 Gupta A, et al., The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol. 2008 Jan;28(1):397-409
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory