Tg(tetO-Creb1*S133A)1Rdu
Transgene Detail
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| Symbol: |
Tg(tetO-Creb1*S133A)1Rdu |
| Name: |
transgene insertion 1, Ronald S Duman |
| MGI ID: |
MGI:3767676 |
| Synonyms: |
TetOp-mCREB |
| Transgene: |
Tg(tetO-Creb1*S133A)1Rdu Location: unknown
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| Alliance: |
Tg(tetO-Creb1*S133A)1Rdu page
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| Strain of Origin: |
C57BL/6 x SJL
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: A rat Creb1 cDNA was mutated at codon 133 to alter the endcoded serine to an alanine. In addition, a FLAG-tag peptide was added at the N-terminus to distinguish the expressed protein from the endogenous protein. The modified cDNA was cloned into an expression vector containing a tetracycline responsive element (TetOP) and a CMV minimal promoter.
(J:128620)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:128620 Nakagawa S, et al., Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. J Neurosci. 2002 May 1;22(9):3673-82 |
| All: |
4 reference(s) |
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Analysis Tools
