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Gene Expression Data
Assay Details
Assay
Reference: J:2076 Simeone A, et al., Nested expression domains of four homeobox genes in developing rostral brain [see comments]. Nature. 1992 Aug 20;358(6388):687-90
Assay type: RNA in situ
MGI Accession ID: MGI:3767590
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Results
Specimen 1g: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 1g/g' Expression is detectable in very anterior regions, including the headfold.
Specimen 1h: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 1h/h' Expression domain contains that of Otx1.
TS13: future prosencephalon Present 1h/h' Expression domain includes the entire forebrain.
Specimen 1i: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future brain Present Regionally restricted 1i/i' Expression domain contains that of Otx1.
TS14: prosencephalon Present 1i/i' Expression domain includes the entire forebrain.
Specimen 1j: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 1j/j' Dorsal expression includes lamina terminalis and presumptive striatum. Posterior boundary coincides with that of the mesencephalon. Ventral expression in diencephalon and mesencephalon; anterior boundary just posterior to optic chiasma.
TS15: future midbrain Present Regionally restricted 1j/j' Dorsal expression includes lamina terminalis and presumptive striatum. Posterior boundary coincides with that of the mesencephalon. Ventral expression in diencephalon and mesencephalon; anterior boundary just posterior to optic chiasma.
TS15: telencephalon Present Regionally restricted 1j/j' Dorsal expression includes lamina terminalis and presumptive striatum. Posterior boundary coincides with that of the mesencephalon. Ventral expression in diencephalon and mesencephalon; anterior boundary just posterior to optic chiasma.
Specimen 2d: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future forebrain Present Regionally restricted 2d/d' Expression in entire forebrain and midbrain.
TS16: future midbrain Present Regionally restricted 2d/d' Expression in entire forebrain and midbrain.
TS16: eye Present Regionally restricted 2d/d' No expression in region of optic chiasma.
TS16: optic recess Absent 2d/d'
Specimen 2h: embryonic day 10.25 (more )
Structure Level Pattern Image Note
TS17: forebrain Present Regionally restricted 2h/h' Expression in entire forebrain and midbrain.
TS17: midbrain Present Regionally restricted 2h/h' Expression in entire forebrain and midbrain.
TS17: eye Present Regionally restricted 2h/h' No expression in region of optic chiasma.
TS17: optic recess Absent 2h/h'
Specimen 2l: embryonic day 10.25 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 2l/l'
Specimen 3d: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3d/d'
Specimen 3g: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3g/g'
Specimen 3i: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3i/i'
Specimen 3m: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3m/m'
TS16: optic cup Present 3m/m'
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory