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Gene Expression Data
Assay Details
Assay
Reference: J:2076 Simeone A, et al., Nested expression domains of four homeobox genes in developing rostral brain [see comments]. Nature. 1992 Aug 20;358(6388):687-90
Assay type: RNA in situ
MGI Accession ID: MGI:3767589
Gene symbol: Otx1
Gene name: orthodenticle homeobox 1
Results
Specimen not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen 1d: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 1d Expressed in a large region of the anterior neural tube.

Specimen 1e: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future diencephalon Present Regionally restricted 1e Dorsal expression includes telencephalon, diencephalon and mesencephalon; posterior boundary coincides with that of mesencephalon. Ventral expression includes diencephalon and mesencephalon with sharp anterior and posterior boundaries.
TS14: future midbrain Present Regionally restricted 1e Dorsal expression includes telencephalon, diencephalon and mesencephalon; posterior boundary coincides with that of mesencephalon. Ventral expression includes diencephalon and mesencephalon with sharp anterior and posterior boundaries.
TS14: prosencephalon Present Regionally restricted 1e Dorsal expression includes telencephalon, diencephalon and mesencephalon; posterior boundary coincides with that of mesencephalon. Ventral expression includes diencephalon and mesencephalon with sharp anterior and posterior boundaries.

Specimen 1f: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 1f Dorsal expression includes telencephalon, diencephalon and mesencephalon; strong expression extends halfway along mesencephalon. Ventral expression includes diencephalon and mesencephalon with sharp anterior and posterior boundaries.
TS15: future midbrain Present Regionally restricted 1f Dorsal expression includes telencephalon, diencephalon and mesencephalon; strong expression extends halfway along mesencephalon. Ventral expression includes diencephalon and mesencephalon with sharp anterior and posterior boundaries.
TS15: telencephalon Present Regionally restricted 1f Dorsal expression includes telencephalon, diencephalon and mesencephalon; strong expression extends halfway along mesencephalon. Ventral expression includes diencephalon and mesencephalon with sharp anterior and posterior boundaries.

Specimen 2c: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: diencephalon Present Regionally restricted 2c Expression domain includes part of telencephalon, diencephalon and mesencephalon, with anterior boundary probably coinciding with that between telencephalon and diencephalon. Strong expression extends only halfway along mesencephalon.
TS16: future midbrain Present Regionally restricted 2c Expression domain includes part of telencephalon, diencephalon and mesencephalon, with anterior boundary probably coinciding with that between telencephalon and diencephalon. Strong expression extends only halfway along mesencephalon.
TS16: telencephalon Present Regionally restricted 2c Expression domain includes part of telencephalon, diencephalon and mesencephalon, with anterior boundary probably coinciding with that between telencephalon and diencephalon. Strong expression extends only halfway along mesencephalon.

Specimen 2g: embryonic day 10.25 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 2g Expression domain includes part of telencephalon, diencephalon and mesencephalon, with anterior boundary probably coinciding with that between telencephalon and diencephalon. Strong expression extends only halfway along mesencephalon.
TS17: midbrain Present Regionally restricted 2g Expression domain includes part of telencephalon, diencephalon and mesencephalon, with anterior boundary probably coinciding with that between telencephalon and diencephalon. Strong expression extends only halfway along mesencephalon.
TS17: telencephalon Present Regionally restricted 2g Expression domain includes part of telencephalon, diencephalon and mesencephalon, with anterior boundary probably coinciding with that between telencephalon and diencephalon. Strong expression extends only halfway along mesencephalon.

Specimen 2k: embryonic day 10.25 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 2k Posterior boundary of expression coincides with that of the mesencephalon.

Specimen 3c: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3c
TS16: embryo ectoderm Present Regionally restricted 3c Expression in ectodermal localizations around the olfactory placodes.

Specimen 3f: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3f

Specimen 3h: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3h

Specimen 3l: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 3l
TS16: optic cup Present 3l


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory