Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Ascl1-EGFP,-cre)1Jejo
Name:	transgene insertion 1, Jane Johnson
MGI ID:	MGI:3767431
Synonyms:	Ascl1-GIC, M1-GIC, Tg(RPCI-428P21-EGFP,-cre)1Jejo
Transgene:	Tg(Ascl1-EGFP,-cre)1Jejo  Location: unknown
Alliance:	Tg(Ascl1-EGFP,-cre)1Jejo page

Strain of Origin:

(C57BL/6 x DBA)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Ascl1-EGFP,-cre)1Jejo expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Ascl1 (MGI:96919)   Mutation details: The transgene is a bacterial artificial chromosome (BAC), RPCI-428P2, bearing a 305 kb mouse genomic segment that contains the Ascl1 locus(98 kb of 5' and 206 kb of 3' of the start codon), in which the coding sequence of the gene has been replaced with an EGFP-IRES-CRE cassette. The GFP reporter expression is low but reflects the Ascl1 pattern throughout multiple stages and in multiple regions, including the caudal neural tube, the telencephalon and diencephalon, and sympathetic and enteric nervous systems. (J:98830, J:117032)

Activity:	Tissue activity of this recombinase allele
Driver:	Ascl1 (mouse) Summary of all recombinase alleles driven by Ascl1. Comparative matrix view of recombinase activities Alliance mouse Ascl1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:98830 Helms AW, et al., Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons. Development. 2005 Jun;132(12):2709-19
All:	8 reference(s)