Tg(CAAG-Ace*H413K*H417K)1Gnk
Transgene Detail
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| Symbol: |
Tg(CAAG-Ace*H413K*H417K)1Gnk |
| Name: |
transgene insertion 1, Gen Kondoh |
| MGI ID: |
MGI:3714634 |
| Transgene: |
Tg(CAAG-Ace*H413K*H417K)1Gnk Location: unknown
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| Alliance: |
Tg(CAAG-Ace*H413K*H417K)1Gnk page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CAAG-Ace*H413K*H417K)1Gnk expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Ace (MGI:87874) |
Transgene codes for a protein with two histidine to lysine mutations. |
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Mutation details: Expression of the mouse Ace gene coding for a protein which contains the amino acid substitutions H413K and H417K is driven by the CAAG promoter which is a fusion of the cytomegalovirus immediate-early enhancer and chicken beta-actin promoter.
(J:122541, J:128288)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:128288 Deguchi E, et al., Dipeptidase-inactivated tACE action in vivo: selective inhibition of sperm-zona pellucida binding in the mouse. Biol Reprod. 2007 Nov;77(5):794-802 |
| All: |
2 reference(s) |
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