Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nr2e1tm2Gsc
Name:	nuclear receptor subfamily 2, group E, member 1; targeted mutation 2, Gunther Schutz
MGI ID:	MGI:3764730
Synonyms:	tlxflox
Gene:	Nr2e1  Location: Chr10:42437959-42459628 bp, - strand  Genetic Position: Chr10, 22.89 cM
Alliance:	Nr2e1tm2Gsc page

Germline Transmission:	Earliest citation of germline transmission: J:127237
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 2 was flanked by loxP sites and an FRT-flanked neo cassette was inserted. The FRT-flanked neo cassette was removed by a subsequent cross to Tg(ACTFLPe)9205Dym mice. (J:127237)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr2e1 Mutation:	32 strains or lines available

Original:	J:127237 Belz T, et al., Inactivation of the gene for the nuclear receptor tailless in the brain preserving its function in the eye. Eur J Neurosci. 2007 Oct;26(8):2222-7
All:	4 reference(s)