Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Alb-Ggcx)1Dgi
Name:	transgene insertion 1, David Ginsburg
MGI ID:	MGI:3763546
Transgene:	Tg(Alb-Ggcx)1Dgi  Location: unknown
Alliance:	Tg(Alb-Ggcx)1Dgi page

Strain of Origin:

C57BL/6 and SJL

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Alb-Ggcx)1Dgi expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Ggcx (MGI:1927655)   Mutation details: A mouse albumin (Alb) promoter drives expression of the murine Ggcx transgene including the entire coding sequence. An internal ribosome entry site sequence (IRES) followed by an enhanced green fluorescent protein (EGFP) coding sequence and a bacterial kanamycin resistant gene (KAN) were also built into the cassette. A chimeric intron with optimized splice signals from the pCI expression vector was also introduced upstream of the Ggcx cDNA in the transgene cassette to enhance gene expression. Expression of Ggcx is liver-specific. The EGFP is not expressed. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)