Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(HSA*LR)20bCath
Name:	transgene insertion 20b, Charles A Thornton
MGI ID:	MGI:3763907
Synonyms:	HSALR, HSALR20b, HSALR-CTG250, LR20b
Transgene:	Tg(HSA*LR)20bCath  Location: unknown
Alliance:	Tg(HSA*LR)20bCath page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(HSA*LR)20bCath expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human ACTA1 (58) Acta1  (MGI:87902)   Mutation details: The transgene contains human HSA with an expanded (250 repeats) CTG inserted into the last exon. Seven lines were created with expression restricted to skeletal muscle. This line contains 2 transgene insertions. (J:64493)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:64493 Mankodi A, et al., Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat [see comments]. Science. 2000 Sep 8;289(5485):1769-73
All:	34 reference(s)