Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Mmp14sabe Name: matrix metallopeptidase 14 (membrane-inserted); small and bugged-eyed MGI ID: MGI:3763359 Gene: Mmp14  Location: Chr14:54669055-54679913 bp, + strand  Genetic Position: Chr14, 27.79 cM Alliance: Mmp14sabe page

Mmp14sabe/Mmp14sabe mouse (right) is small and short-nosed Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

C57BL/6J

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A C to T transition in Chromosome 14 bapse pair 54,436,154 (GRCm38) is predicted to cause a p.R92C mutation directly adjacent to a critical cysteine in the cysteine switch regulatory domain. (J:127164, J:223062) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mmp14 Mutation:	43 strains or lines available

Original:	J:127164 Curtain MM, et al., A possible new mutation to Mmp 14. MGI Direct Data Submission. 2007;
All:	2 reference(s)