Tg(Gt(ROSA)26Sor-EGFP)I1Able
Transgene Detail
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| Symbol: |
Tg(Gt(ROSA)26Sor-EGFP)I1Able |
| Name: |
transgene insertion I1, Andrew B Leiter |
| MGI ID: |
MGI:3763223 |
| Synonyms: |
ROSA26-EGFP, ROSA26-EGFP BAC |
| Transgene: |
Tg(Gt(ROSA)26Sor-EGFP)I1Able Location: unknown
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| Alliance: |
Tg(Gt(ROSA)26Sor-EGFP)I1Able page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The bacterial artificial chromosome (BAC) clone RP23-401D9 containing the mouse Gt(ROSA)26Sor gene (and 153 kb of upstream and 15 kb of downstream sequence) was modified by inserting a red-shifted variant Enhanced Green Fluorescent Protein (EGFP; Clontech No. 6029-1) cDNA and polyadenylation sequence at nucleotide 521 of the first exon of transcript 1. Founders with a single copy of the transgene (founder line I1) were maintained on a CD-1 background. EGFP is ubiquitously and reproducibly expressed in all tissues and organs examined. Stable and uniform EGFP expression is observed in differentiated progeny of transplanted hematopoietic stem cells (HSC) isolated from ROSA26-EGFP mice.
(J:126166)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 3 strains available
Cell Lines: 0 lines available
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| Original: |
J:126166 Giel-Moloney M, et al., Ubiquitous and uniform in vivo fluorescence in ROSA26-EGFP BAC transgenic mice. Genesis. 2007 Feb;45(2):83-9 |
| All: |
5 reference(s) |
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Analysis Tools
