Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Thy1-Syt1/ECFP)1Sud
Name:	transgene insertion 1, Thomas C Sudhof
MGI ID:	MGI:3762948
Synonyms:	Syt1 transgenic, Tg(Thy1-Syt1-ECFP)1Sud, TMC
Transgene:	Tg(Thy1-Syt1/ECFP)1Sud  Location: unknown
Alliance:	Tg(Thy1-Syt1/ECFP)1Sud page

Strain of Origin:

(C57BL/6 x SJL)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: A transgenic vector was designed to create a rat synaptotagmin 1/enhanced cyan fluorescent protein (ECFP) fusion protein under the control of a mouse Thy1 promoter lacking exon3 and the flanking introns (to make gene expression neuron-specific). Expression is detected only in the brain with fluorescence observed throughout the brain, marking synaptic vesicles. (J:105052)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:105052 Han W, et al., C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. J Biol Chem. 2005 Feb 11;280(6):5089-100
All:	1 reference(s)