Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Mylpf-cre)3Kraj
Name:	transgene insertion 3, Stan Krajewski
MGI ID:	MGI:3761931
Synonyms:	CRE3, MLC2v-CRE3, MLCcre
Transgene:	Tg(Mylpf-cre)3Kraj  Location: unknown
Alliance:	Tg(Mylpf-cre)3Kraj page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Mylpf-cre)3Kraj expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note rat Myl11 (24584) Mylpf  (MGI:97273)   Mutation details: A 250-bp fragment of the rat ventricular light chain II gene (Mylpf) was used as promoter to drive expression of the cre recombinase cDNA. Crosses of these mice were made to mice (dh4) carrying a transgenic reporter gene (a dominant-hygR gene separated from a constitutive PGK promoter by a loxP-flanked PGK-neo cassette; cre recombination results in generation of the active-hygR allele detected by PCR). Line 3 was determined to express cre selectively in the brain. (J:99342)

Activity:	Tissue activity of this recombinase allele
Driver:	Myl11 (rat) Summary of all recombinase alleles driven by Myl11. Comparative matrix view of recombinase activities Alliance rat Myl11 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:99342 Banares S, et al., Novel pan-neuronal Cre-transgenic line for conditional ablation of genes in the nervous system. Genesis. 2005 May;42(1):6-16
All:	6 reference(s)