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Tg(TcrbHsv2.3)L118-3Cbn
Transgene Detail
Summary
Symbol: Tg(TcrbHsv2.3)L118-3Cbn
Name: transgene insertion L118-3, Frank Carbone
MGI ID: MGI:3761647
Synonyms: gBT-I.3
Transgene: Tg(TcrbHsv2.3)L118-3Cbn  Location: unknown  
Alliance: Tg(TcrbHsv2.3)L118-3Cbn page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(TcrbHsv2.3)L118-3Cbn expresses 1 gene
 
Mutation detailsRearranged Tcra and Tcrb derived from HSV-1 glycoprotein B specific CTL clone HSV2.3 were placed under the control of a 2 kb fragment of the H-2Kb and a 700 bp fragment including the Igh enhancer. The two constructs were coinjected into F1 embryo zygotes resulting in the establishment of two founder lines. In line L118-3, the two constructs appear to have integrated on separate chromosomes. After backcrossing to C57BL/6, the mouse line referred to as gBT-I.3 was established. This line contains two separately named transgenes. (J:124700)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:124700 Mueller SN, et al., Characterization of two TCR transgenic mouse lines specific for herpes simplex virus. Immunol Cell Biol. 2002 Apr;80(2):156-63
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory