Tg(TcrbHsv2.3)L118-3Cbn
Transgene Detail
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Symbol: |
Tg(TcrbHsv2.3)L118-3Cbn |
Name: |
transgene insertion L118-3, Frank Carbone |
MGI ID: |
MGI:3761647 |
Synonyms: |
gBT-I.3 |
Transgene: |
Tg(TcrbHsv2.3)L118-3Cbn Location: unknown
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Alliance: |
Tg(TcrbHsv2.3)L118-3Cbn page
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Strain of Origin: |
Not Applicable
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(TcrbHsv2.3)L118-3Cbn expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Tcrb (MGI:98578) |
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Mutation details: Rearranged Tcra and Tcrb derived from HSV-1 glycoprotein B specific CTL clone HSV2.3 were placed under the control of a 2 kb fragment of the H-2Kb and a 700 bp fragment including the Igh enhancer. The two constructs were coinjected into F1 embryo zygotes resulting in the establishment of two founder lines. In line L118-3, the two constructs appear to have integrated on separate chromosomes. After backcrossing to C57BL/6, the mouse line referred to as gBT-I.3 was established. This line contains two separately named transgenes.
(J:124700)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:124700 Mueller SN, et al., Characterization of two TCR transgenic mouse lines specific for herpes simplex virus. Immunol Cell Biol. 2002 Apr;80(2):156-63 |
All: |
4 reference(s) |
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