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Gene Expression Data
Assay Details
Assay
Reference: J:17695 Roberts CW, et al., Hox11 controls the genesis of the spleen. Nature. 1994 Apr 21;368(6473):747-9
Assay type: RNA in situ
MGI Accession ID: MGI:3760080
Gene symbol: Tlx1
Gene name: T cell leukemia, homeobox 1
Probe: Hox11 cDNA
Probe preparation: Antisense RNA
Results
Specimen 2a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal mesogastrium Present Regionally restricted 2a Expression is present within a highly localized portion of the splanchnic mesoderm.
TS19: cranial ganglion Present Regionally restricted 2a Expression is present within the branchial motor nuclei in the hindbrain.
TS19: 3rd branchial groove Present 2a
Specimen 2b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal mesogastrium Present Regionally restricted 2b Expression is present within the splanchnic mesoderm where mesenchymal cells are beginning to condense on the dorsolateral margin of the future stomach, the site of the splenic primordium.
Specimen 2c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal mesogastrium Strong Regionally restricted 2c There is strong expression in the splenic primordium.
Specimen 2d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal mesogastrium Strong Regionally restricted 2d Expression is present in the mesenchymal cells of the splenic primordium.
TS20: pancreas Absent 2d
TS20: stomach Absent 2d
Specimen 2e: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal mesogastrium Present Regionally restricted 2e Expression is present in the splenic primordium.
Specimen 2f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spleen primordium Present 2f Expression in the spleen is markedly weaker than at previous times.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory