Gene Expression Data
Assay Details
Assay
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Reference:
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J:124438
Poirier K, et al., Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). Hum Mutat. 2007 Nov;28(11):1055-64
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3759489
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Gene symbol:
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Tuba1a
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Gene name:
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tubulin, alpha 1A
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Probe:
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Tuba1a cDNA
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
E16.5:
embryonic day 16.5
(more )
Specimen
E16.5:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
P10:
postnatal day 10
(more )
Specimen
P10:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS28: brain |
Present |
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3D
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Expression is observed in all brain regions.
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TS28: cerebral cortex |
Present |
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3G
,
3D
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This is one of the structures with the most intense expression levels.
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TS28: brainstem |
Present |
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3D
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This is one of the structures with the most intense expression levels.
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TS28: cerebellum |
Present |
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3D
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This is one of the structures with the most intense expression levels.
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TS28: hippocampus |
Present |
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3D
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This is one of the structures with the most intense expression levels.
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TS28: rostral migratory stream |
Present |
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3D
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Some of the most intense expression is found in the rostral migratory stream.
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Specimen
Older postnatal:
postnatal
(more )
Specimen
Older postnatal:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS28: brain |
Present |
|
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At postnatal ages later than P20 and adult stages, expression levels significantly decrease.
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TS28: hippocampus |
Weak |
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A low level of expression persists in the hippocampus.
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TS28: rostral migratory stream |
Weak |
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A low level of expression persists in the rostral migratory stream.
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