About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:89669 Langa F, et al., Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice. Eur J Neurosci. 2003 Oct;18(8):2188-96
Assay type: Northern blot
MGI Accession ID: MGI:3759469
Gene symbol: Sigmar1
Gene name: sigma non-opioid intracellular receptor 1
Probe: pmcS1/N
Probe preparation: Double stranded labelled with P32 DNA
Visualized with: Autoradiography
Results Image: 2B
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
Liver +/+ P adult TS28: liver Present 15 µg; total RNA Not Specified Not Specified
Liver +/- P adult TS28: liver Present (a) 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1+Not Specified
Liver -/- P adult TS28: liver Absent 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1tm1LmonNot Specified
Kidney +/+ P adult TS28: metanephros Present 15 µg; total RNA Not Specified Not Specified
Kidney +/- P adult TS28: metanephros Present (a) 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1+Not Specified
Kidney -/- P adult TS28: metanephros Absent 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1tm1LmonNot Specified
Brain +/+ P adult TS28: brain Present 15 µg; total RNA Not Specified Not Specified
Brain +/- P adult TS28: brain Present (a) 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1+Not Specified
Brain -/- P adult TS28: brain Absent 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1tm1LmonNot Specified
Heart +/+ P adult TS28: heart Present 15 µg; total RNA Not Specified Not Specified
Heart +/- P adult TS28: heart Present (a) 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1+Not Specified
Heart -/- P adult TS28: heart Absent 15 µg; total RNA either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) Sigmar1tm1Lmon/Sigmar1tm1LmonNot Specified
Notes:
(a) Expression was reduced to about half the wild-type levels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory