Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	B3gat1tm1Tkaw
Name:	beta-1,3-glucuronyltransferase 1; targeted mutation 1, Toshisuke Kawasaki
MGI ID:	MGI:3759445
Synonyms:	GlcAT-P-
Gene:	B3gat1  Location: Chr9:26644813-26672646 bp, + strand  Genetic Position: Chr9, 11.49 cM, cytoband A4
Alliance:	B3gat1tm1Tkaw page

Germline Transmission:	Earliest citation of germline transmission: J:125254
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4 and 5 were replaced with a neo cassette disrupting domains critical for glucoronyltransferasse activity to create a null allele. The absence of transcript was confirmed by a northern blot using mRNA extracted from the brains of 10 week old mice. (J:125254)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any B3gat1 Mutation:	14 strains or lines available

Original:	J:125254 Yamamoto S, et al., Mice deficient in nervous system-specific carbohydrate epitope HNK-1 exhibit impaired synaptic plasticity and spatial learning. J Biol Chem. 2002 Jul 26;277(30):27227-31
All:	6 reference(s)