Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:87330
Nakamura T, et al., The Kruppel-like factor epiprofin is expressed by epithelium of developing teeth, hair follicles, and limb buds and promotes cell proliferation. J Biol Chem. 2004 Jan 2;279(1):626-34
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:3759254
|
|
Gene symbol:
|
Sp6
|
|
Gene name:
|
trans-acting transcription factor 6
|
|
Probe:
|
Epiprofin probe
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
Visualized with:
|
Alkaline phosphatase
|
|
|
Results
|
Specimen
3A:
embryonic day 11.5
(more  )
Specimen
3A:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 11.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: 1st branchial arch |
Present |
Regionally restricted |
3A
|
Expression is present in the dental epithelium.
|
Specimen
3B:
embryonic day 12.5
(more )
Specimen
3B:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: mandibular process |
Present |
Regionally restricted |
3B
|
Expression is present in the incipient incisors.
|
Specimen
3C:
embryonic day 13.5
(more )
Specimen
3C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
3D:
embryonic day 14.5
(more )
Specimen
3D:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
4E:
embryonic day 12.5
(more )
Note: This molar is at the bud/cap stage.
Specimen
4E:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This molar is at the bud/cap stage.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: tooth |
Present |
Regionally restricted |
4E
|
In this molar, expression is present in the inner dental epithelium but not other parts of dental tissues.
|
Specimen
4F:
embryonic day 14.5
(more )
Note: This molar is at the cap stage.
Specimen
4F:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This molar is at the cap stage.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: molar epithelium |
Present |
Regionally restricted |
4F
|
Expression is present in the inner dental epithelium but not other parts of dental tissues.
|
| TS22: inner enamel epithelium |
Present |
|
4F
|
Expression is present in the inner dental epithelium but not other parts of dental tissues.
|
Specimen
4G:
embryonic day 17.5
(more )
Note: This molar is at the early bell stage.
Specimen
4G:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 17.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This molar is at the early bell stage.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS25: molar epithelium |
Present |
Regionally restricted |
4G
|
Expression is present in the inner dental epithelium but not other parts of dental tissues.
|
| TS25: inner enamel epithelium |
Present |
|
4G
|
Expression is present in the inner dental epithelium but not other parts of dental tissues.
|
Specimen
4H:
embryonic day 19.5
(more )
Note: This molar is at the late bell stage.
Specimen
4H:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 19.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This molar is at the late bell stage.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: molar epithelium |
Present |
Regionally restricted |
4H
|
Expression is present in the inner enamel epithelium (preameloblast/ameloblasts).
|
| TS26: inner enamel epithelium |
Present |
Regionally restricted |
4H
|
Expression is present in the inner enamel epithelium (preameloblast/ameloblasts).
|
| TS26: molar dental papilla |
Weak |
Regionally restricted |
4H
|
Expression is seen in differentiated odontoblasts.
|
Specimen
5B:
postnatal newborn
(more )
Specimen
5B:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
postnatal newborn
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: incisor epithelium |
Present |
Regionally restricted |
5B
,
5E
|
Expression is present in the dental epithelium of the cervical loop starting from the early stage to the secretory stage of ameloblasts.
|
| TS27: cervical loop |
Present |
|
5E
,
5B
|
Expression is present in the dental epithelium of the cervical loop starting from the early stage to the secretory stage of ameloblasts.
|
| TS27: incisor dental papilla |
Present |
Regionally restricted |
5B
,
5E
|
Expression is seen in mesenchymal odontoblasts.
|
Specimen
6A:
embryonic day 18.5
(more )
Specimen
6A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
6D:
embryonic day 18.5
(more )
Note: This is a coronal section.
Specimen
6D:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This is a coronal section.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: hair follicle |
Strong |
|
6D
|
There is strong expression in the proliferating epithelium of the inner root sheath in the matrix of hair follicles.
|
| TS26: hair root sheath |
Strong |
|
6D
|
There is strong expression in the proliferating epithelium of the inner root sheath in the matrix of hair follicles.
|
Specimen
7A:
embryonic day 8.5
(more )
Specimen
7A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 8.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS14: caudal neuropore |
Present |
Regionally restricted |
7A
|
Expression is present transiently in the caudal/posterior neuropore.
|
Specimen
7B:
embryonic day 9.5
(more )
Specimen
7B:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
7C:
embryonic day 10.5
(more )
Specimen
7C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
7D:
embryonic day 11.5
(more )
Specimen
7D:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 11.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
7E:
embryonic day 12.5
(more )
Specimen
7E:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: foot epithelium |
Present |
Regionally restricted |
7E
|
Expression is present in the specific areas of the apical ectoderm.
|
| TS20: hand epithelium |
Present |
Regionally restricted |
7E
|
Expression is present in the specific areas of the apical ectoderm.
|
Specimen
7F:
embryonic day 10.5
(more )
Specimen
7F:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
7G:
embryonic day 11.5
(more )
Specimen
7G:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 11.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
7H:
embryonic day 12.5
(more )
Specimen
7H:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: forelimb digit epithelium |
Present |
Regionally restricted |
7H
|
Expression is reduced and restricted to specific areas of the apical ectodermal ridge of the digits.
|
Specimen
7I:
embryonic day 13.5
(more )
Specimen
7I:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forelimb digit epithelium |
Present |
Regionally restricted |
7I
|
Expression is reduced and restricted to specific areas of the apical ectodermal ridge of the digits.
|
Specimen
7J:
embryonic day 14.5
(more )
Specimen
7J:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
Not shown:
embryonic day 14.5
(more )
Specimen
Not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: foot |
Absent |
|
|
|
|
Analysis Tools