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Gene Expression Data
Assay Details
Assay
Reference: J:74050 Arend LJ, et al., Mouse beta(6) integrin sequence, pattern of expression, and role in kidney development. J Am Soc Nephrol. 2000 Dec;11(12):2297-305
Assay type: RNA in situ
MGI Accession ID: MGI:3758857
Gene symbol: Itgb6
Gene name: integrin beta 6
Probe: Itgb6 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical renal tubule Present 7B Expression is in the proximal convoluted tubule and loop of Henle and is weak in the superficial cortical nephrogenic zone.
TS25: metanephros Present 7B Expression is in the proximal convoluted tubule and loop of Henle and is weak in the superficial cortical nephrogenic zone.
TS25: renal proximal tubule Present 7B Expression is in the proximal convoluted tubule and loop of Henle and is weak in the superficial cortical nephrogenic zone.

Specimen 7C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: renal proximal tubule Strong 7C
TS25: cortical renal tubule Strong Regionally restricted 7C Expression is in the loop of Henle.
TS25: renal distal tubule Weak 7C
TS25: metanephros Present Regionally restricted 7C Expression is adjacent to some capillary-stage glomeruli, possibly in macula densa.
TS25: renal cortex Present Regionally restricted 7C Absent in comma- and S-shaped bodies and in undifferentiated mesenchyme.
TS25: glomerular tuft Absent 7C Absent within capillary-stage glomeruli.

Specimen 7D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: renal proximal tubule Strong 7D
TS25: cortical renal tubule Strong Regionally restricted 7D Expression is in the loop of Henle.
TS25: renal distal tubule Weak 7D
TS25: metanephros Present Regionally restricted 7D Expression is adjacent to some capillary-stage glomeruli, possibly in macula densa.
TS25: renal cortex Present Regionally restricted 7D Absent in comma- and S-shaped bodies and in undifferentiated mesenchyme.
TS25: glomerular tuft Absent 7D Absent within capillary-stage glomeruli.

Specimen 7E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: renal proximal tubule Strong 7E
TS25: cortical renal tubule Strong Regionally restricted 7E Expression is in the loop of Henle.
TS25: renal distal tubule Weak 7E
TS25: metanephros Present Regionally restricted 7E Expression is adjacent to some capillary-stage glomeruli, possibly in macula densa.
TS25: renal cortex Present Regionally restricted 7E Absent in comma- and S-shaped bodies and in undifferentiated mesenchyme.
TS25: glomerular tuft Absent 7E

Specimen 7F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: renal proximal tubule Strong 7F
TS25: cortical renal tubule Strong Regionally restricted 7F Expression is in the loop of Henle.
TS25: renal distal tubule Present 7F
TS25: metanephros Present Regionally restricted 7F Expression is adjacent to some capillary-stage glomeruli, possibly in macula densa.
TS25: renal cortex Present Regionally restricted 7F Absent in comma- and S-shaped bodies and in undifferentiated mesenchyme.
TS25: glomerular tuft Absent 7F

Specimen 8A: embryonic day 17.5 (more )
Note: Double labeled: dark blue - Itgb6; brown - Dolichos biflorus.
Structure Level Pattern Image Note
TS25: renal proximal tubule Present 8A
TS25: cortical renal tubule Present Regionally restricted 8A Expression is in the loop of Henle.
TS25: collecting duct Absent 8A

Specimen 8B: embryonic day 17.5 (more )
Note: Double labeled: dark blue - Itgb6; brown - Dolichos biflorus.
Structure Level Pattern Image Note
TS25: renal proximal tubule Present 8B
TS25: cortical renal tubule Present Regionally restricted 8B Expression is in the loop of Henle.
TS25: collecting duct Absent 8B

Specimen 8C: embryonic day 17.5 (more )
Note: Double labeled: dark blue - Itgb6; brown - Lotus tetragonolobus-peroxidase conjugate.
Structure Level Pattern Image Note
TS25: renal proximal tubule Present 8C
TS25: cortical renal tubule Present Regionally restricted 8C Expression is in the loop of Henle.

Specimen 8D: embryonic day 17.5 (more )
Note: Double labeled: dark blue - Itgb6; brown - Lotus tetragonolobus-peroxidase conjugate.
Structure Level Pattern Image Note
TS25: renal proximal tubule Present 8D
TS25: cortical renal tubule Present Regionally restricted 8D Expression is in the loop of Henle.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory