Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Apoc3)5381Bres
Name:	transgene insertion 5381, Jan L Breslow
MGI ID:	MGI:3758464
Synonyms:	MoCIIITg
Transgene:	Tg(Apoc3)5381Bres  Location: unknown
Alliance:	Tg(Apoc3)5381Bres page

Strain of Origin:

C57BL/6 x CBA

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Apoc3)5381Bres expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Apoc3 (MGI:88055)   Mutation details: A genomic construct containing a 4.7 kb Xbal-Xbal fragment, which includes the entire mouse apoC-III gene plus 2 kb of 5' and 1 kb of 3' sequence, was used for the transgene. Northern blot and densitometry analysis showed that Apoc3 mRNA was increased 4-fold in liver and 5-fold in the intestine. (J:34875)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:34875 Aalto-Setala K, et al., Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice. J Lipid Res. 1996 Aug;37(8):1802-11
All:	1 reference(s)