Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Eqtntm1Gar
Name:	equatorin, sperm acrosome associated; targeted mutation 1, David L Garbers
MGI ID:	MGI:3723138
Synonyms:	SSTM
Gene:	Eqtn  Location: Chr4:94795504-94817080 bp, - strand  Genetic Position: Chr4, 43.34 cM, cytoband C5
Alliance:	Eqtntm1Gar page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exons 4-7 with a neomycin resistance cassette and a thymidine kinase (TK) gene. Western blotting revealed the complete absence of protein in homozygous mutant testes. Immunohistochemical analysis and immunofluorescence confirmed the absence of detectable protein in homozygous mutant sperm. (J:101977, J:219150)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Eqtn Mutation:	23 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	2 reference(s)