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Gene Expression Data
Assay Details
Assay
Reference: J:46162 Chen ZL, et al., Expression of neuropsin mRNA in the mouse embryo and the pregnant uterus. J Histochem Cytochem. 1998 Mar;46(3):313-20
Assay type: RNA in situ
MGI Accession ID: MGI:3722896
Gene symbol: Klk8
Gene name: kallikrein related-peptidase 8
Probe: Nrpn cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 4.5 (more )
Structure Level Pattern Image Note
TS6: blastocyst-stage conceptus Absent No signal above background was observed in the implanting blastocyst.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Absent No signal above background was observed in the E4.5 uterus.

Specimen 2AB: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS28: decidua Present 2AB Expression was detected in the primary decidual zone.

Specimen 2CD: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 2CD Strong expression in both antimesometrial and glycogen-rich regions surrounding the embryo.

Specimen 2EF: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 2EF Strong expression in both antimesometrial and glycogen-rich regions surrounding the embryo.

Specimen 2GH: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 2GH Expression was reduced and dispersed in the antimesometrial region. Maximum expression in the glycogen-rich region of decidua.

Specimen 2IJ: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 2IJ Expression only in a layer of decidual cells facing the placental labyrinth.

Specimen 3A: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS28: decidua Present 3A
TS9: primary trophoblast giant cell Absent 3A

Specimen 3B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS28: decidua Present 3B
TS16: extraembryonic component Absent 3B No expression in trophoblast giant cells

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Weak Regionally restricted Low levels of expression in the developing heart.
TS15: primitive ventricle Present Regionally restricted Expression in the trabeculae of the ventricle.
TS15: heart atrium Absent Little or no expression in the atrium.

Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Present 4A
TS20: lung Present 4A
TS20: pituitary gland Present 4A
TS20: thymus primordium Present 4A
TS20: choroid plexus Present Regionally restricted 4A Expression in epithelial cells of the choroid plexus.
TS20: skin Present Regionally restricted 4A Expression in skin of the facial area.

Specimen 4BC: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart ventricle Present Regionally restricted 4BC Expression in the trabeculae of the ventricle increased.
TS20: heart atrium Absent 4BC

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present Expression in the pituitary and thymus was unchanged.
TS22: thymus primordium Present Expression in the pituitary and thymus was unchanged.
TS22: heart Weak Expression in the heart and lung decreased.
TS22: lung Weak Expression in the heart and lung decreased.

Specimen 4D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thymus Present Regionally restricted 4D Expression restricted to areas coinciding with precursors of the thymic medullary core.
TS24: heart Trace 4D Expression was hardly detectable in heart or lungs.
TS24: lung Trace 4D Expression was hardly detectable in heart or lungs.
TS24: skin Present Regionally restricted 4D Expression extended throughout the skin of the entire body. Prominent expression in regions where the skin folded and thickened, e.g. in the regions of the snout, oral orifice, and developing limbs.

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: heart Absent Authors report that expression was undetectable in heart, lung, pituitary and thymus.
TS26: lung Absent Authors report that expression was undetectable in heart, lung, pituitary and thymus.
TS26: pituitary gland Absent Authors report that expression was undetectable in heart, lung, pituitary and thymus.
TS26: thymus Absent Authors report that expression was undetectable in heart, lung, pituitary and thymus.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Absent
TS28: thymus Absent

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: skin Weak 5A

Specimen 5B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: skin Present 5B Expression in skin gradually increased.

Specimen 5C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: skin Present 5C Expression in skin gradually increased, localized in suprabasal cells (granule and spinous cells). Expression in a subpopulation of suprabasal keratinocytes that migrate toward the surface while undergoing differentiation. No expression in basal cells.

Specimen 5D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: skin Strong Regionally restricted 5D Peak expression in skin, localized in suprabasal cells (granule and spinous cells) No expression in basal cells.

Specimen 5E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epidermis granular layer Present 5E Decreased expression in skin, localized in suprabasal cells (granule and spinous cells)
TS28: epidermis spinous layer Present 5E Decreased expression in skin, localized in suprabasal cells (granule and spinous cells)
TS28: epidermis basal layer Absent 5E

Specimen 6A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb skin Strong Regionally restricted 6A Strong expression in limbs, especially in regions between the digits.

Specimen 6B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb skin Strong Regionally restricted 6B Strong expression in limbs, especially in regions between the digits.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted Expression forestomach.
TS20: stomach epithelium Present Regionally restricted Expression in mucosal epithelium with keratinocytes

Specimen 7A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: stomach Present Regionally restricted 7A Expression forestomach.
TS24: stomach epithelium Present Regionally restricted 7A Expression in mucosal epithelium with keratinocytes

Specimen 7B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: stomach epithelium Present Regionally restricted 7B Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.

Specimen 7C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach proventricular region Present 7C

Specimen 7D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach epithelium Strong Regionally restricted 7D Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.

Specimen 7F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: tongue epithelium Strong Regionally restricted 7F Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.

Specimen 7G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: esophagus epithelium Strong Regionally restricted 7G Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory