Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:46162
Chen ZL, et al., Expression of neuropsin mRNA in the mouse embryo and the pregnant uterus. J Histochem Cytochem. 1998 Mar;46(3):313-20
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:3722896
|
Gene symbol:
|
Klk8
|
Gene name:
|
kallikrein related-peptidase 8
|
Probe:
|
Nrpn cDNA
|
Probe preparation:
|
Antisense labelled with S35 RNA
|
Visualized with:
|
Autoradiography
|
|
Results
|
Specimen
not shown:
embryonic day 4.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 4.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
postnatal adult
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: uterus |
Absent |
|
|
No signal above background was observed in the E4.5 uterus.
|
Specimen
2AB:
embryonic day 5.5
(more )
Specimen
2AB:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 5.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: decidua |
Present |
|
2AB
|
Expression was detected in the primary decidual zone.
|
Specimen
2CD:
embryonic day 6.5
(more )
Specimen
2CD:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 6.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: decidua |
Strong |
Regionally restricted |
2CD
|
Strong expression in both antimesometrial and glycogen-rich regions surrounding the embryo.
|
Specimen
2EF:
embryonic day 8.5
(more )
Specimen
2EF:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 8.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: decidua |
Strong |
Regionally restricted |
2EF
|
Strong expression in both antimesometrial and glycogen-rich regions surrounding the embryo.
|
Specimen
2GH:
embryonic day 10.0
(more )
Specimen
2GH:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 10.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: decidua |
Present |
Regionally restricted |
2GH
|
Expression was reduced and dispersed in the antimesometrial region. Maximum expression in the glycogen-rich region of decidua.
|
Specimen
2IJ:
embryonic day 11.5
(more )
Specimen
2IJ:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: decidua |
Present |
Regionally restricted |
2IJ
|
Expression only in a layer of decidual cells facing the placental labyrinth.
|
Specimen
3A:
embryonic day 6.5
(more )
Specimen
3A:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 6.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3B:
embryonic day 10.0
(more )
Specimen
3B:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 10.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 9.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: heart |
Weak |
Regionally restricted |
|
Low levels of expression in the developing heart.
|
TS15: primitive ventricle |
Present |
Regionally restricted |
|
Expression in the trabeculae of the ventricle.
|
TS15: heart atrium |
Absent |
|
|
Little or no expression in the atrium.
|
Specimen
4A:
embryonic day 12.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
4BC:
embryonic day 12.5
(more )
Specimen
4BC:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 14.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 14.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: pituitary gland |
Present |
|
|
Expression in the pituitary and thymus was unchanged.
|
TS22: thymus primordium |
Present |
|
|
Expression in the pituitary and thymus was unchanged.
|
TS22: heart |
Weak |
|
|
Expression in the heart and lung decreased.
|
TS22: lung |
Weak |
|
|
Expression in the heart and lung decreased.
|
Specimen
4D:
embryonic day 16.5
(more )
Specimen
4D:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 16.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: thymus |
Present |
Regionally restricted |
4D
|
Expression restricted to areas coinciding with precursors of the thymic medullary core.
|
TS24: heart |
Trace |
|
4D
|
Expression was hardly detectable in heart or lungs.
|
TS24: lung |
Trace |
|
4D
|
Expression was hardly detectable in heart or lungs.
|
TS24: skin |
Present |
Regionally restricted |
4D
|
Expression extended throughout the skin of the entire body. Prominent expression in regions where the skin folded and thickened, e.g. in the regions of the snout, oral orifice, and developing limbs.
|
Specimen
not shown:
embryonic day 18.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: heart |
Absent |
|
|
Authors report that expression was undetectable in heart, lung, pituitary and thymus.
|
TS26: lung |
Absent |
|
|
Authors report that expression was undetectable in heart, lung, pituitary and thymus.
|
TS26: pituitary gland |
Absent |
|
|
Authors report that expression was undetectable in heart, lung, pituitary and thymus.
|
TS26: thymus |
Absent |
|
|
Authors report that expression was undetectable in heart, lung, pituitary and thymus.
|
Specimen
not shown:
postnatal adult
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
5A:
embryonic day 12.5
(more )
Specimen
5A:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: skin |
Weak |
|
5A
|
|
Specimen
5B:
embryonic day 14.5
(more )
Specimen
5B:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 14.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: skin |
Present |
|
5B
|
Expression in skin gradually increased.
|
Specimen
5C:
embryonic day 16.5
(more )
Specimen
5C:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 16.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: skin |
Present |
|
5C
|
Expression in skin gradually increased, localized in suprabasal cells (granule and spinous cells). Expression in a subpopulation of suprabasal keratinocytes that migrate toward the surface while undergoing differentiation. No expression in basal cells.
|
Specimen
5D:
embryonic day 18.5
(more )
Specimen
5D:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: skin |
Strong |
Regionally restricted |
5D
|
Peak expression in skin, localized in suprabasal cells (granule and spinous cells) No expression in basal cells.
|
Specimen
5E:
postnatal adult
(more )
Specimen
5E:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
6A:
embryonic day 15.5
(more )
Specimen
6A:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 15.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: forelimb skin |
Strong |
Regionally restricted |
6A
|
Strong expression in limbs, especially in regions between the digits.
|
Specimen
6B:
embryonic day 15.5
(more )
Specimen
6B:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 15.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: forelimb skin |
Strong |
Regionally restricted |
6B
|
Strong expression in limbs, especially in regions between the digits.
|
Specimen
not shown:
embryonic day 12.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: stomach |
Present |
Regionally restricted |
|
Expression forestomach.
|
TS20: stomach epithelium |
Present |
Regionally restricted |
|
Expression in mucosal epithelium with keratinocytes
|
Specimen
7A:
embryonic day 16.5
(more )
Specimen
7A:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 16.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: stomach |
Present |
Regionally restricted |
7A
|
Expression forestomach.
|
TS24: stomach epithelium |
Present |
Regionally restricted |
7A
|
Expression in mucosal epithelium with keratinocytes
|
Specimen
7B:
embryonic day 16.5
(more )
Specimen
7B:
(close )
Genetic Background:
|
DDY
|
Age:
|
embryonic day 16.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: stomach epithelium |
Present |
Regionally restricted |
7B
|
Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.
|
Specimen
7C:
postnatal adult
(more )
Specimen
7C:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7D:
postnatal adult
(more )
Specimen
7D:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: stomach epithelium |
Strong |
Regionally restricted |
7D
|
Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.
|
Specimen
7F:
postnatal adult
(more )
Specimen
7F:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: tongue epithelium |
Strong |
Regionally restricted |
7F
|
Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.
|
Specimen
7G:
postnatal adult
(more )
Specimen
7G:
(close )
Genetic Background:
|
DDY
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: esophagus epithelium |
Strong |
Regionally restricted |
7G
|
Expression in mucosal epithelium, localized to suprabasal cell layers close to the basal cell layer.
|
|