Tg(TcraHsv2.3,TcrbHsv2.3)L118-1Cbn
Transgene Detail
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| Symbol: |
Tg(TcraHsv2.3,TcrbHsv2.3)L118-1Cbn |
| Name: |
transgene insertion L118-1, Frank Carbone |
| MGI ID: |
MGI:3722258 |
| Synonyms: |
gBT-I, (gB)T-I.1, gBT-I.1 |
| Transgene: |
Tg(TcraHsv2.3,TcrbHsv2.3)L118-1Cbn Location: unknown
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| Alliance: |
Tg(TcraHsv2.3,TcrbHsv2.3)L118-1Cbn page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcraHsv2.3,TcrbHsv2.3)L118-1Cbn expresses
2 genes
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Mutation details: Rearranged Tcra and Tcrb derived from HSV-1 glycoprotein B specific CTL clone HSV2.3 were placed under the control of a 2 kb fragment of the H-2Kb and a 700 bp fragment including the Igh enhancer. The two constructs were coinjected into F1 embryo zygotes resulting in the establishment of two founder lines. In line L118-1 the two constructs appear to have cointegrated at one site. After backcrossing to C57BL/6, the mouse line referred to as gBT-I.1 was established.
(J:124700, J:124701)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:124700 Mueller SN, et al., Characterization of two TCR transgenic mouse lines specific for herpes simplex virus. Immunol Cell Biol. 2002 Apr;80(2):156-63 |
| All: |
40 reference(s) |
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Analysis Tools
