Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Col2a1-cre/ERT)1Flng
Name:	transgene insertion 1, Fanxin Long
MGI ID:	MGI:3721223
Synonyms:	Col2-creTM
Transgene:	Tg(Col2a1-cre/ERT)1Flng  Location: unknown
Alliance:	Tg(Col2a1-cre/ERT)1Flng page

Strain of Origin:

(C57BL/6J x CBA/J)F1

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Col2a1-cre/ERT)1Flng expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Col2a1   Mutation details: The procollagen, type II, alpha 1 promoter was used to drive expression of cre recombinase in chondrocytes versus perichondrial cells upon proper administration of tamoxifen. (J:123971)

Activity:	Tissue activity of this recombinase allele
Driver:	Col2a1 (species not specified) Summary of all recombinase alleles driven by Col2a1. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:123971 Hilton MJ, et al., Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage. Dev Biol. 2007 Aug 1;308(1):93-105
All:	6 reference(s)