Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: C5ar2tm1Gdy Name: complement component 5a receptor 2; targeted mutation 1, George D Yancopoulos MGI ID: MGI:3721065 Synonyms: C5L2 KO, VG100 Gene: C5ar2  Location: Chr7:15968512-15978079 bp, - strand  Genetic Position: Chr7, 8.77 cM Alliance: C5ar2tm1Gdy page

Hepatic steatosis in C3tm1Crr/C3tm1Crr and C5ar2tm1Gdy/C5ar2tm1Gdy mice following partial hepatectomy Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:102090
Parent Cell Line:	F1H4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NTac)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Velocigene technology was used to delete a 1 kb portion of the gene and introduce a lacZ reporter gene. (J:102090)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any C5ar2 Mutation:	18 strains or lines available

Original:	J:102090 Valenzuela DM, et al., High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat Biotechnol. 2003 Jun;21(6):652-9
All:	6 reference(s)