Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cdk5tm1Bibb
Name:	cyclin dependent kinase 5; targeted mutation 1, James A Bibb
MGI ID:	MGI:3720892
Synonyms:	fCDK5
Gene:	Cdk5  Location: Chr5:24623239-24628528 bp, - strand  Genetic Position: Chr5, 11.73 cM, cytoband A3-B1
Alliance:	Cdk5tm1Bibb page

Germline Transmission:	Earliest citation of germline transmission: J:124046
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted to flank exons 2-5, the exons encoding the vital catalytic-domain components. (J:124046)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

12 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdk5 Mutation:	15 strains or lines available

Original:	J:124046 Hawasli AH, et al., Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat Neurosci. 2007 Jul;10(7):880-6
All:	18 reference(s)