Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tg(Itgax-cre,-EGFP)4097Ach
Name:	transgene insertion 4097, Alexander V Chervonsky
MGI ID:	MGI:3720729
Synonyms:	CD11c-Cre, CD11c-Cre 4907, CD11c-Cre-GFP, CD11c-Cre-GFP.4097, Tg(Itgax-cre,EGFP)4097Ach
Transgene:	Tg(Itgax-cre,-EGFP)4097Ach  Location: unknown
Alliance:	Tg(Itgax-cre,-EGFP)4097Ach page

Strain of Origin:

C57BL/6J

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Itgax-cre,-EGFP)4097Ach expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Itgax   Mutation details: The Itgax promoter and enchancer were used to drive cre expression in a pIRES2-EGFP-based plasmid. Two lines were created with line 4097 exhibiting greater expression than 4272 in dendritic cells. (J:123556)

Activity:	Tissue activity of this recombinase allele
Driver:	Itgax (species not specified) Summary of all recombinase alleles driven by Itgax.

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 5 strains available      Cell Lines: 0 lines available

Original:	J:123556 Stranges PB, et al., Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007 May;26(5):629-41
All:	85 reference(s)