Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Aicdatm1(cre)Mnz
Name:	activation-induced cytidine deaminase; targeted mutation 1, Michel C Nussenzweig
MGI ID:	MGI:3720568
Synonyms:	AID-, AIDCre, AID Cre
Gene:	Aicda  Location: Chr6:122530768-122541139 bp, + strand  Genetic Position: Chr6, 57.65 cM, cytoband F2
Alliance:	Aicdatm1(cre)Mnz page

Germline Transmission:	Earliest citation of germline transmission: J:153206
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Aicdatm1(cre)Mnz expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Aicda (MGI:1342279)   Mutation details: A targeting vector containing Cre, an FRT-flanked neomycin resistance cassette, and a DTA (diphtheria toxin) gene was used to replace exon 1 of the gene. (J:145691, J:153206)

Activity:	Tissue activity of this recombinase allele
Driver:	Aicda (mouse) Summary of all recombinase alleles driven by Aicda. Alliance mouse Aicda gene page

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Aicdatm1(cre)Mnz

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aicda Mutation:	55 strains or lines available

Original:	J:153206 Nussenzweig MC, Generation of an Aicda knock-in cre allele. MGI Direct Data Submission. 2009;
All:	42 reference(s)