Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Igk-Aicda)14Mnz
Name:	transgene insertion 14, Michel C Nussenzweig
MGI ID:	MGI:3720492
Synonyms:	IgkAID, VkAID tg
Transgene:	Tg(Igk-Aicda)14Mnz  Location: unknown
Alliance:	Tg(Igk-Aicda)14Mnz page

Strain of Origin:

C57BL/6 x CBA

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Igk-Aicda)14Mnz expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Aicda (MGI:1342279)   Mutation details: The coding sequence for the Aicda (activation-induced cytidine deaminase) gene is driven by the mouse immunoglobulin kappa light chain promoter (Igk) in this transgene. The construct was injected into C57BL/6 x (C57BL/6 x CBA) embryos. Founder line number 14 was generated. (J:154731)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:154731 Robbiani DF, et al., AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol Cell. 2009 Nov 25;36(4):631-41
All:	5 reference(s)