Gene Expression Data
Assay Details
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Assay
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Reference:
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J:123454
McLaughlin D, et al., Specific modification of heparan sulphate is required for normal cerebral cortical development. Mech Dev. 2003 Dec;120(12):1481-8
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:3720001
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Gene symbol:
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Hs2st1
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Gene name:
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heparan sulfate 2-O-sulfotransferase 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1A:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Hs2st1Gt(pGT1.8TM)ST125Nimr/Hs2st1+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Hs2st1Gt(pGT1.8TM)ST125Nimr/Hs2st1+
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: telencephalon |
Present |
Graded |
1B
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Expression is highest in the medial wall of the telencephalon and decreases in a dorsal-ventral gradient.
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| TS22: cerebral cortex |
Present |
Graded |
1B
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Expression is present throughout the dorsal cortex, with an apparent gradient decreasing in the dorso-ventral axis.
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| TS22: ganglionic eminence |
Strong |
Regionally restricted |
1B
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Expression is present in the ventricular zone of the ganglionic eminence.
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| TS22: thalamus |
Weak |
Regionally restricted |
1B
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Faint expression is seen in the extreme medial part of the thalamus; it is not detected in the body of the thalmus.
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Analysis Tools
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