Tg(Ckm-DGAT2)10Far
Transgene Detail
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| Symbol: |
Tg(Ckm-DGAT2)10Far |
| Name: |
transgene insertion 10, Bob Farese |
| MGI ID: |
MGI:3717406 |
| Synonyms: |
MCK-DGAT2 |
| Transgene: |
Tg(Ckm-DGAT2)10Far Location: unknown
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| Alliance: |
Tg(Ckm-DGAT2)10Far page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Ckm-DGAT2)10Far expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
DGAT2 (84649) |
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Mutation details: The targeting construct was designed with 4 kb of the mouse muscle creatine kinase (MCK) promoter sequence placed upstream of a 1.2 kb human acyl-CoA:diacylglycerol acyltransferase 2 (DGAT2) cDNA sequence, followed by a 2.2 kb human growth hormone minigene (providing the polyA signal). The transgene was microinjected into C57BL/6NHsd fertilized eggs and the resulting transgenic offspring were bred to C57BL/6NHsd. Founder line 10 mice were established.
(J:129495)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:129495 Levin MC, et al., Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1772-81 |
| All: |
1 reference(s) |
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Analysis Tools
