Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Rpgrip1ltm1Urt
Name:	Rpgrip1-like; targeted mutation 1, Ulrich Ruther
MGI ID:	MGI:3716208
Synonyms:	Ftm-
Gene:	Rpgrip1l  Location: Chr8:91943658-92039890 bp, - strand  Genetic Position: Chr8, 44.29 cM
Alliance:	Rpgrip1ltm1Urt page

Germline Transmission:	Earliest citation of germline transmission: J:122745
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeted mutation was desgned to replace exons 4 and 5 with a PGK-neo cassette. The result was a truncated protein lacking all functional domains except the first coiled-coil domain. (J:122745)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

23 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rpgrip1l Mutation:	57 strains or lines available

Original:	J:122745 Vierkotten J, et al., Ftm is a novel basal body protein of cilia involved in Shh signalling. Development. 2007 Jul;134(14):2569-77
All:	13 reference(s)